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p16 (BPM6238) Mouse mAb (PBS Only)
db30195-PBS
Datasheet

Product Name : p16 (BPM6238) Mouse mAb (PBS Only)

Cat.No.: db30195-PBS

Synonyms : ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A

Application:

Reactivity : Human

Host species : Mouse

Conjugation/Formulation:PBS Only

  • Background The progression of cells through the cell cycle is regulated by a family of protein kinases known as cyclin-dependent kinases (Cdks). The sequential activation of individual members of this family and their consequent phosphorylation of critical substrates promotes orderly progression through the cell cycle. Moreover, the gene encoding p16 INK4A exhibits a high frequency of homozygous deletions and point mutations in established human tumor cell lines.
  • Immunogen Full length recombinant p16 INK4A of human origin was used as an immunogen
  • Swiss Prot P42771
  • Synonyms ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A
  • Reactivity Human
  • Application IHC
  • Calculated MW 17 kDa
  • Host species Mouse
  • Clonality Monoclonal
  • Clonality No. BPM6238
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Immunohistochemistry of paraffin-embedded human cervical intraepithelial neoplasias using p16 antibody at dilution of 1:200 (200x lens).
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  • 货期:现货
For research use only. Not intended for diagnostic.