AFP (BP6244) Rabbit mAb (PBS Only)
Product Name :
AFP (BP6244) Rabbit mAb (PBS Only)
Cat.No.:
db30200-PBS
Synonyms :
AFPD; FETA; HPAFP
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. While AFP expression in adult cells is low, it is aberrantly expressed in adult liver cancer cells. The tumor suppressor gene p53 and β?catenin are both involved in the regulation of AFP expression. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma.
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Immunogen
Synthetic peptide. This information is proprietary to Biolynx
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Swiss Prot
P02771
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Synonyms
AFPD; FETA; HPAFP
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Reactivity
Human
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Application
IHC
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Calculated MW
67 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
BP6244
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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可询价
- 货期：现货
For research use only. Not intended for diagnostic.
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