Cellular Apoptosis Susceptibility Rabbit pAb - diagbio | 戴格生物

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Cellular Apoptosis Susceptibility Rabbit pAb

db4488

年底大促

Datasheet

Product Name : Cellular Apoptosis Susceptibility Rabbit pAb

Cat.No.: db4488

Synonyms : CAS; CSE1; XPO2

Application：

Reactivity : Human, Mouse

Host species : Rabbit

Un-conjugated

Background Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Immunogen A synthetic peptide of human Cellular Apoptosis Susceptibility
Gene ID 1434
Swiss Prot P55060
Synonyms CAS; CSE1; XPO2
Reactivity Human, Mouse
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:1000-1:5000
IHC: 1:50
ICC/IF: 1:100
FC: 1:20
Calculated MW 110 kDa
Observed MW 110 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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