CD43 Rabbit pAb - diagbio | 戴格生物

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CD43 Rabbit pAb

db4890

年底大促

Datasheet

Product Name : CD43 Rabbit pAb

Cat.No.: db4890

Synonyms : LSN; CD43; GALGP; GPL115; LEU-22

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
Immunogen Recombinant protein of human CD43
Gene ID 6693
Swiss Prot P16150
Synonyms LSN; CD43; GALGP; GPL115; LEU-22
Reactivity Human
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:1000
IHC: 1:500
ICC/IF: 1:20
FC: 1:20
Calculated MW 40 kDa
Observed MW 115 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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