BCR Rabbit pAb - diagbio | 戴格生物

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BCR Rabbit pAb

db4893

年底大促

Datasheet

Product Name : BCR Rabbit pAb

Cat.No.: db4893

Synonyms : ALL; CML; PHL; BCR1; D22S11; D22S662

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human BCR
Gene ID 613
Swiss Prot P11274
Synonyms ALL; CML; PHL; BCR1; D22S11; D22S662
Reactivity Human, Mouse, Rat
Application WB, IHC, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:100
FC: 1:100
IP: 1:20
Calculated MW 143 kDa
Observed MW 150 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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