GEN1 Rabbit pAb - diagbio | 戴格生物

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GEN1 Rabbit pAb

db5151

Datasheet

Product Name : GEN1 Rabbit pAb

Cat.No.: db5151

Synonyms : Gen

Application：

Reactivity : Human, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
Immunogen A synthetic peptide of human GEN1
Gene ID 348654
Swiss Prot Q17RS7
Synonyms Gen
Reactivity Human, Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 103 kDa
Observed MW 103 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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