Syntrophin alpha 1 Rabbit pAb
Product Name :
Syntrophin alpha 1 Rabbit pAb
Cat.No.:
db5640
Synonyms :
SNT1; LQT12; TACIP1; dJ1187J4.5
Reactivity :
Human, Mouse
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
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Background
Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013]
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Immunogen
A synthetic peptide of human Syntrophin alpha 1
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Gene ID
6640
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Swiss Prot
Q13424
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Synonyms
SNT1; LQT12; TACIP1; dJ1187J4.5
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Reactivity
Human, Mouse
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Application
WB, IHC, ICC/IF, FC
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Recommended dilution
WB: 1:1000-1:5000
IHC: 1:50
ICC/IF: 1:50
FC: 1:50
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Calculated MW
54 kDa
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Observed MW
54 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
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