Product Name :
GSDMA Rabbit pAb
Cat.No.:
db5731
Synonyms :
GSDM; FKSG9; GSDM1
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
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Background
May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).
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Immunogen
Recombinant protein of human GSDMA
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Gene ID
284110
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Swiss Prot
Q96QA5
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Synonyms
GSDM; FKSG9; GSDM1
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Reactivity
Human, Mouse, Rat
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Application
WB
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Recommended dilution
WB: 1:1000
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Calculated MW
49 kDa
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Observed MW
49 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
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