uPA Receptor/U-PAR Rabbit pAb - diagbio | 戴格生物

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uPA Receptor/U-PAR Rabbit pAb

db5822

年底大促

Datasheet

Product Name : uPA Receptor/U-PAR Rabbit pAb

Cat.No.: db5822

Synonyms : CD87; UPAR; URKR; U-PAR

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human uPA Receptor/U-PAR
Gene ID 5329
Swiss Prot Q03405
Synonyms CD87; UPAR; URKR; U-PAR
Reactivity Human
Application ICC/IF, FC, IP
Recommended dilution ICC/IF: 1:20
FC: 1:50
IP: 1:20
Calculated MW 37 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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