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Fas (4C3) Mouse mAb (PBS Only)
db6064-PBS
Datasheet
Product Name : Fas (4C3) Mouse mAb (PBS Only)
Cat.No.: db6064-PBS
Synonyms : FAS; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6
Application：
Reactivity : Human
Host species : Mouse
Conjugation/Formulation：PBS Only
- Background Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
- Immunogen Purified recombinant human FAS (C-terminus) protein fragments expressed in E.coli
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Gene ID
355
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Swiss Prot
P25445
- Synonyms FAS; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6
- Reactivity Human
- Application WB
- Calculated MW 38 kDa
- Observed MW 45 kDa
- Host species Mouse
- Clonality Monoclonal
- Clonality No. 4C3-G7-B7-H5
- Isotype IgG1
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of FAS(Cterminus) in Jurkat lysates using FAS(Cterminus) antibody.
订购信息
- Package Price (RMB)
- 可询价
- 货期：现货
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For research use only. Not intended for diagnostic.
