Cyclin D2 (6E11) Mouse mAb (PBS Only) - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

Cyclin D2 (6E11) Mouse mAb (PBS Only)

db6075-PBS

Datasheet

Product Name : Cyclin D2 (6E11) Mouse mAb (PBS Only)

Cat.No.: db6075-PBS

Synonyms : KIAK0002

Application：

Reactivity : Human

Host species : Mouse

Conjugation/Formulation：PBS Only

Un-conjugated PBS Only

Background The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and Ticular tumors. Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3).
Immunogen Purified recombinant human Cyclin D2 protein fragments expressed in E.coli
Gene ID 894
Swiss Prot P30279
Synonyms KIAK0002
Reactivity Human
Application WB
Calculated MW 33 kDa
Observed MW 38 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 6E11-G6-F5
Isotype IgG2b
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/mL
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot analysis of Cyclin D2 in CHO-K1 lysates and CHO-K1 transfected by Cyclin D2fragment EGFP fusion proteinlysates using Cyclin D2 antibody.

订购信息

Package Price (RMB)
可询价
货期：现货