CRK (3H7) Mouse mAb (PBS Only)
Product Name :
CRK (3H7) Mouse mAb (PBS Only)
Cat.No.:
db6158-PBS
Synonyms :
p38; CRKII
Reactivity :
Human
Host species :
Mouse
Conjugation/Formulation:PBS Only
-
Background
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
-
Immunogen
Purified recombinant human CrkII protein fragments expressed in E.coli
-
Gene ID
1398
-
Swiss Prot
P46108
-
Synonyms
p38; CRKII
-
Reactivity
Human
-
Application
WB
-
Calculated MW
34 kDa
-
Observed MW
34 kDa
-
Host species
Mouse
-
Clonality
Monoclonal
-
Clonality No.
3H7-E5-H8
-
Isotype
IgG2b
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Concentration
1 mg/mL
-
Formulation
PBS Only
-
Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
-
Western blot analysis of CrkII in Lncap, A431, MCF-7 and HT-1080 lysates using CrkII antibody.
订购信息
-
Package
Price (RMB)
-
可询价
- 货期:现货
For research use only. Not intended for diagnostic.