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Smad2 (6H5) Mouse mAb (PBS Only)
db6171-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases.Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and,on formation of the SMAD2/SMAD4 complex,activates transcription.May act as a tumor suppressor in colorectal carcinoma.Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
- Immunogen Purified recombinant human Smad2 protein fragments expressed in E.coli
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Gene ID
4087
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Swiss Prot
Q15796
- Synonyms JV18;MADH2;MADR2;JV18-1;hMAD-2;hSMAD2
- Reactivity Human, Mouse
- Application WB, ICC/IF
- Calculated MW 52 kDa
- Observed MW 60 kDa
- Host species Mouse
- Clonality Monoclonal
- Clonality No. 6H5-E3-C11
- Isotype IgG1
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of Smad2 in Hela, A431, Jurkat and K562 lysates using Smad2 antibody. -
Immunocytochemistry analysis of Smad2 (6H5) in HeLa using Smad2 antibody. -
Western blot analysis of Smad2 (6H5) in 3T3 lysates using Smad2 antibody.
订购信息
- Package Price (RMB)
- 可询价
- 货期：现货
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For research use only. Not intended for diagnostic.
