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Bax (2B12) Mouse mAb (PBS Only)
db6205-PBS
Datasheet

Product Name : Bax (2B12) Mouse mAb (PBS Only)

Cat.No.: db6205-PBS

Synonyms : Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4

Application:

Reactivity : Human, Monkey

Host species : Mouse

Conjugation/Formulation:PBS Only

  • Background Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
  • Immunogen Purified recombinant human Bax protein fragments expressed in E.coli
  • Gene ID 581
  • Swiss Prot Q07812
  • Synonyms Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4
  • Reactivity Human, Monkey
  • Application WB
  • Calculated MW 21 kDa
  • Observed MW 21 kDa
  • Host species Mouse
  • Clonality Monoclonal
  • Clonality No. 2B12-G6-H6
  • Isotype IgG2a
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Western blot analysis of Bax in COS7, Raji, CEM and Hela lysates using Bax antibody.
订购信息
  • Package Price (RMB)
  • 可询价
  • 货期:现货
For research use only. Not intended for diagnostic.