Product Name : STAT3 (4C8) Mouse mAb (PBS Only)
Cat.No.: db6208-PBS
Synonyms : STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor
Reactivity : Human, Mouse, Rat, Monkey, Hamster
Host species : Mouse
Conjugation/Formulation：PBS Only
- Background Signal transducer and transcription activator that mediates cellular responses to interleukins,KITLG/SCF and other growth factors.May mediate cellular responses to activated FGFR1,FGFR2,FGFR3 and FGFR4.Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes.Activated by IL31 through IL31RA.Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity.Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G by similarity.
- Immunogen Purified recombinant human STAT3 protein fragments expressed in E.coli
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Gene ID
6774
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Swiss Prot
P40763
- Synonyms STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor
- Reactivity Human, Mouse, Rat, Monkey, Hamster
- Application WB
- Recommended dilution WB: 1:500-1:1000
- Calculated MW 88 kDa
- Observed MW 88 kDa
- Host species Mouse
- Clonality Monoclonal
- Clonality No. 4C8-1C9-H8
- Isotype IgG1
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of STAT3 in CHO-K1, C6, 3T3, K562, CEM, Jurkat, Hela, MCF-7, COS7, 293T, A431 and A549 lysates using STAT3 antibody.
- Package Price (RMB)
- 可询价
- 货期：可询价
