Rad23B (5H1) Mouse mAb - diagbio | 戴格生物

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Rad23B (5H1) Mouse mAb

db6213

Datasheet

Product Name : Rad23B (5H1) Mouse mAb

Cat.No.: db6213

Synonyms : P58; HR23B; HHR23B

Application：

Reactivity : Human, Mouse, Rat, Monkey, Hamster

Host species : Mouse

Un-conjugated

Background The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Immunogen Purified recombinant human hHR23b protein fragments expressed in E.coli
Gene ID 5887
Swiss Prot P54727
Synonyms P58; HR23B; HHR23B
Reactivity Human, Mouse, Rat, Monkey, Hamster
Application WB, ICC/IF, IHC-Fr, IHC-P
Recommended dilution WB: 1:500-1:1000
IHC: 1:50-1:100
ICC/IF: 1:50-1:200
Calculated MW 43 kDa
Observed MW 58 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 5H1-A10-A7
Isotype IgG2b
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.

Western blot analysis of hHR23b in A431, K562, Jurkat, C6, 3T3 and Hela lysates using hHR23b antibody.
Immunocytochemistry analysis of Rad23B (5H1) in HeLa using hHR23b antibody.
Immunohistochemistry analysis of paraffin-embedded Prostate Cancer using hHR23b antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Western blot analysis of Rad23B (5H1) in K562, SW480, CHO-K1, 3T3 and COS7 lysates using Rad23B (5H1) antibody

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