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Caspase-9 (1D1) Mouse mAb (PBS Only)
db6217-PBS
Datasheet

Product Name : Caspase-9 (1D1) Mouse mAb (PBS Only)

Cat.No.: db6217-PBS

Synonyms : CASP9; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6

Application:

Reactivity : Human

Host species : Mouse

Conjugation/Formulation:PBS Only

  • Background Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
  • Immunogen Purified recombinant human Caspase-9 protein fragments expressed in E.coli
  • Gene ID 842
  • Swiss Prot P55211
  • Synonyms CASP9; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6
  • Reactivity Human
  • Application WB
  • Calculated MW 46 kDa
  • Observed MW 49,37 kDa
  • Host species Mouse
  • Clonality Monoclonal
  • Clonality No. 1D1-F2-E9
  • Isotype IgG1
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Western blot analysis of Caspase9 in A549, MCF-7, Jurkat, K562 and Hela lysates using Caspase9 antibody.
订购信息
  • Package Price (RMB)
  • 可询价
  • 货期:现货
For research use only. Not intended for diagnostic.