Product Name :
Ku70 (7B1) Mouse mAb
Cat.No.:
db6220
Synonyms :
ML8; KU70; TLAA; CTC75; CTCBF; G22P1
Reactivity :
Human, Monkey
Host species :
Mouse
Conjugation/Formulation:Un-conjugated
-
Background
It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.
-
Immunogen
Purified recombinant human Ku70 protein fragments expressed in E.coli
-
Gene ID
2547
-
Swiss Prot
P12956
-
Synonyms
ML8; KU70; TLAA; CTC75; CTCBF; G22P1
-
Reactivity
Human, Monkey
-
Application
WB, ICC/IF, IP, ChIP
-
Recommended dilution
WB: 1:500-1:1000
ICC/IF: 1:50-1:200
IP: 1:20
ChIP: 1:20
-
Calculated MW
70 kDa
-
Observed MW
67 kDa
-
Host species
Mouse
-
Clonality
Monoclonal
-
Clonality No.
7B1-E12-G4
-
Isotype
IgG1
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.
×
-
Western blot analysis of Ku70 in Hela, A549, COS7 and K562 lysates using Ku70 antibody.
-
Immunocytochemistry analysis of Ku70 (7B1) in HeLa using Ku70 antibody.
-
Immunoprecipitation analysis of Ku70 (7B1) in Hela lysates using Ku7 antibody.
订购信息
-
Package
Price (RMB)
-
50μL
1398
-
100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.