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Ku70 (7B1) Mouse mAb

Product Name : Ku70 (7B1) Mouse mAb

Cat.No.: db6220

Synonyms : ML8; KU70; TLAA; CTC75; CTCBF; G22P1

Application:

Reactivity : Human, Monkey

Host species : Mouse

Conjugation/Formulation:Un-conjugated

  • Background It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.
  • Immunogen Purified recombinant human Ku70 protein fragments expressed in E.coli
  • Gene ID 2547
  • Swiss Prot P12956
  • Synonyms ML8; KU70; TLAA; CTC75; CTCBF; G22P1
  • Reactivity Human, Monkey
  • Application WB, ICC/IF, IP, ChIP
  • Recommended dilution WB: 1:500-1:1000
    ICC/IF: 1:50-1:200
    IP: 1:20
    ChIP: 1:20
  • Calculated MW 70 kDa
  • Observed MW 67 kDa
  • Host species Mouse
  • Clonality Monoclonal
  • Clonality No. 7B1-E12-G4
  • Isotype IgG1
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.
  • Western blot analysis of Ku70 in Hela, A549, COS7 and K562 lysates using Ku70 antibody.
  • Immunocytochemistry analysis of Ku70 (7B1) in HeLa using Ku70 antibody.
  • Immunoprecipitation analysis of Ku70 (7B1) in Hela lysates using Ku7 antibody.
订购信息
  • Package Price (RMB)
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.