Product Name :
Ku70 (6H10) Mouse mAb
Cat.No.:
db6221
Synonyms :
ML8;KU70;TLAA;CTC75;CTCBF;G22P1
Reactivity :
Human
Host species :
Mouse
Conjugation/Formulation:Un-conjugated
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Background
It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.
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Immunogen
Purified recombinant human Ku70 protein fragments expressed in E.coli
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Gene ID
2547
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Swiss Prot
P12956
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Synonyms
ML8;KU70;TLAA;CTC75;CTCBF;G22P1
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Reactivity
Human
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Application
WB, ICC/IF
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Recommended dilution
WB: 1:500-1:1000
ICC/IF: 1:50-1:200
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Calculated MW
70 kDa
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Observed MW
70 kDa
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Host species
Mouse
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Clonality
Monoclonal
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Clonality No.
6H10-E9-G7
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Isotype
IgG2b
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.
×
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Western blot analysis of Ku70 in Hela, A549, MCF-7, Jurkat and Raji lysates using Ku70 antibody.
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Immunocytochemistry analysis of Ku70 (6H10) in HeLa using Ku70 antibody.
订购信息
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Package
Price (RMB)
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.