Product Name :
EGFR (5E10) Mouse mAb
Cat.No.:
db6227
Synonyms :
ERBB;HER1;mENA;ERBB1;PIG61
Reactivity :
Human, Monkey
Host species :
Mouse
Conjugation/Formulation:Un-conjugated
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Background
EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
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Immunogen
Purified recombinant human EGFR protein fragments expressed in E.coli
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Gene ID
1956
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Swiss Prot
P00533
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Synonyms
ERBB;HER1;mENA;ERBB1;PIG61
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Reactivity
Human, Monkey
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Application
WB, ICC/IF, IP
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Recommended dilution
WB: 1:500-1:1000
ICC/IF: 1:50-1:200
IP: 1:20
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Calculated MW
134 kDa
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Observed MW
175 kDa
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Host species
Mouse
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Clonality
Monoclonal
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Clonality No.
5E10-G10-E11
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Isotype
IgG1
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.
×
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Western blot analysis of EGFR in A549, MDA-MB-468 and COS7 lysates using EGFR antibody.
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Immunocytochemistry analysis of EGFR (5E10) in HeLa using EGFR antibody.
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Immunoprecipitation analysis of EGFR (5E10) in Hela lysates using EGFR antibody.
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Immunocytochemistry analysis of EGFR in MDA-MB-468 cells using EGFR antibody.
订购信息
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Package
Price (RMB)
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.