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EGFR (5E10) Mouse mAb

Product Name : EGFR (5E10) Mouse mAb

Cat.No.: db6227

Synonyms : ERBB;HER1;mENA;ERBB1;PIG61

Application:

Reactivity : Human, Monkey

Host species : Mouse

Conjugation/Formulation:Un-conjugated

  • Background EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
  • Immunogen Purified recombinant human EGFR protein fragments expressed in E.coli
  • Gene ID 1956
  • Swiss Prot P00533
  • Synonyms ERBB;HER1;mENA;ERBB1;PIG61
  • Reactivity Human, Monkey
  • Application WB, ICC/IF, IP
  • Recommended dilution WB: 1:500-1:1000
    ICC/IF: 1:50-1:200
    IP: 1:20
  • Calculated MW 134 kDa
  • Observed MW 175 kDa
  • Host species Mouse
  • Clonality Monoclonal
  • Clonality No. 5E10-G10-E11
  • Isotype IgG1
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.
  • Western blot analysis of EGFR in A549, MDA-MB-468 and COS7 lysates using EGFR antibody.
  • Immunocytochemistry analysis of EGFR (5E10) in HeLa using EGFR antibody.
  • Immunoprecipitation analysis of EGFR (5E10) in Hela lysates using EGFR antibody.
  • Immunocytochemistry analysis of EGFR in MDA-MB-468 cells using EGFR antibody.
订购信息
  • Package Price (RMB)
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.