Phospho-Histone H2A.X (Ser139) (7G9) Mouse mAb (PBS Only)
Product Name :
Phospho-Histone H2A.X (Ser139) (7G9) Mouse mAb (PBS Only)
Cat.No.:
db6251-PBS
Synonyms :
H2AX; H2AFX; H2a/x; HIST5-2AX; Histone H2AX
Reactivity :
Human, Mouse
Host species :
Mouse
Conjugation/Formulation:PBS Only
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Background
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
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Immunogen
Synthetic phosphopeptide corresponding to residues surrounding Ser139 of human H2A.X
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Gene ID
3014
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Swiss Prot
P16104
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Synonyms
H2AX; H2AFX; H2a/x; HIST5-2AX; Histone H2AX
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Reactivity
Human, Mouse
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Application
WB, ICC/IF
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Calculated MW
15 kDa
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Observed MW
15 kDa
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Host species
Mouse
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Clonality
Monoclonal
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Clonality No.
7G9-H4
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Isotype
IgG1
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot analysis of Phosphorylation of H2A.X at Serine 139 in 3T3 or Hydroxyureatreated 3T3 lysates using Phospho-Histone H2A.X (Ser139) antibody.
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Immunofluorescence analysis of Phospho-Histone H2A.X (Ser139) (7G9) in 3T3 or Hydroxyureatreated 3T3 using Phospho-Histone H2A.X (Ser139) antibody.
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Immunofluorescence analysis of Phospho-Histone H2A.X (Ser139) (7G9) in A549(upper, untreated or Hydroxyureatreated) and Hela(lower, untreated or Hydroxyureatreated) using Phospho-Histone H2A.X (Ser139) antibody.
订购信息
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Package
Price (RMB)
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可询价
- 货期:现货
For research use only. Not intended for diagnostic.