Product Name : eIF4E (8C8) Mouse mAb (PBS Only)
Cat.No.: db6264-PBS
Synonyms : EIF4E; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein
Reactivity : Human, Mouse, Rat
Host species : Mouse
Conjugation/Formulation：PBS Only
- Background Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1. Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
- Immunogen Purified recombinant human eif4e protein expressed in E.coli
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Gene ID
1977
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Swiss Prot
P06730
- Synonyms EIF4E; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein
- Reactivity Human, Mouse, Rat
- Application WB
- Calculated MW 25 kDa
- Observed MW 25 kDa
- Host species Mouse
- Clonality Monoclonal
- Clonality No. 8C8-C10-C12
- Isotype IgG1
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of eIF4E in MDA-MB-468, ZR751, MCF-7, T47D and CHO-K1 lysates using eIF4E antibody. -
Western blot analysis of eIF4E (8C8) in Jurkat, Hela, MCF-7, K562, C6, 3T3, PC-12, HepG2, CHO-K1, Raji, Raw264.7 and Ramos lysates using eIF4E antibody.
- Package Price (RMB)
- 可询价
- 货期：现货
