E-Cadherin (6B10) Mouse mAb - diagbio | 戴格生物

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E-Cadherin (6B10) Mouse mAb

db6304

Datasheet

Product Name : E-Cadherin (6B10) Mouse mAb

Cat.No.: db6304

Synonyms : CDH1; CDHE; UVO; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD antigen CD324

Application：

Reactivity : Human, Mouse

Host species : Mouse

Un-conjugated PBS Only

Background Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
Immunogen A synthesized peptide derived from human E-Cadherin
Gene ID 999
Swiss Prot P12830
Synonyms CDH1; CDHE; UVO; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD antigen CD324
Reactivity Human, Mouse
Application WB, IHC-P
Recommended dilution WB: 1:500-1:1000
IHC: 1:50-1:100
Calculated MW 97 kDa
Observed MW 135 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 6B10-F4-G10
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.

Western blot analysis of ECadherin in T47D, HCT116, MDA-MB-468 and Caco2 lysates using ECadherin antibody.
Western blot analysis of E Cadherin (6B10) in mouse embryos and HCT116 lysates using ECadherin antibody.
Immunohistochemistry analysis of paraffin-embedded Human tonsils using ECadherin (6B1) antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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