Product Name : MCM2 (2B5) Mouse mAb (PBS Only)
Cat.No.: db6407-PBS
Synonyms : MCM2; BM28; CCNL1; CDCL1; KIAA0030; DNA replication licensing factor MCM2; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28
Reactivity : Human, Mouse
Host species : Mouse
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
- Immunogen Purified recombinant fragment of human MCM2 expressed in E. Coli
-
Gene ID
4171
-
Swiss Prot
P49736
- Synonyms MCM2; BM28; CCNL1; CDCL1; KIAA0030; DNA replication licensing factor MCM2; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28
- Reactivity Human, Mouse
- Application WB, IHC-Fr, IHC-P, ICC/IF, FC, IP
- Calculated MW 102 kDa
- Observed MW 125 kDa
- Host species Mouse
- Clonality Monoclonal
- Clonality No. 2B5-H4-A9
- Isotype IgG1
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
-
Western blot analysis of MCM2 in Jurkat, K562, 3T3 and Hela lysates using MCM2 antibody. -
Immunoprecipitation analysis of MCM2 (2B5) in Hela lysates using MCM2 antibody. -
Immunofluorescence analysis of MCM2 (2B5) in Hela cells using MCM2 antibody(green),and DAPI (blue). -
Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue using MCM2 (2B5) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. -
Immunohistochemistry analysis of paraffin-embedded ovarian cancer tissues using MCM2 (2B5) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. -
Immunohistochemistry analysis of paraffin-embedded colon cancer tissues using MCM2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
- Package Price (RMB)
- 可询价
- 货期：现货
