GAPDH (8A3) Mouse mAb - diagbio | 戴格生物

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GAPDH (8A3) Mouse mAb

db6497

Datasheet

Product Name : GAPDH (8A3) Mouse mAb

Cat.No.: db6497

Synonyms : G3PD; GAPD; HEL-S-162eP

Application：

WB
ICC/IF
IHC-P

Reactivity : Human, Mouse, Rat, Monkey, Dog, Chicken, Hamster, Rabbit, Pig, Sheep, Insect, Yeast

Host species : Mouse

Conjugation/Formulation：Un-conjugated

Un-conjugated PBS Only

Background Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules . Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
Immunogen Synthetic Peptide of GAPDH
Gene ID 2597
Swiss Prot P04406
Synonyms G3PD; GAPD; HEL-S-162eP
Reactivity Human, Mouse, Rat, Monkey, Dog, Chicken, Hamster, Rabbit, Pig, Sheep, Insect, Yeast
Application WB, ICC/IF, IHC-P
Recommended dilution WB: 1:5000-1:10000
IHC: 1:50-1:200
ICC/IF: 1/100-1:200
Calculated MW 36 kDa
Observed MW 36 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 8A3-6C3-8D6
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.

Western blot analysis of GAPDH in T47D, 3T3, COS7 and C6 lysates using GAPDH antibody.
Immunofluorescence analysis of GAPDH (8A3) in Human tonsil tissue using GAPDH (8A3) antibody.

订购信息

Package Price (RMB)
100μL 1200
500μL 4800
1mL 8600
货期：现货