Product Name :
LC3B (8H6) Mouse mAb
Cat.No.:
db6556
Synonyms :
MAP1LC3B
Reactivity :
Human
Host species :
Mouse
Conjugation/Formulation：Un-conjugated
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Background
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
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Immunogen
Purified recombinant protein expressed in E.coli
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Gene ID
81631
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Swiss Prot
Q9GZQ8
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Synonyms
MAP1LC3B
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Reactivity
Human
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Application
IHC-P
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Recommended dilution
IHC: 1:50-1:100
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Host species
Mouse
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Clonality
Monoclonal
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Clonality No.
8H6-6D10-3A4
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Isotype
IgG1
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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50μL
1398
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100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
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