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MLKL (5E3) Mouse mAb (PBS Only)
db6571-PBS
Datasheet

Product Name : MLKL (5E3) Mouse mAb (PBS Only)

Cat.No.: db6571-PBS

Synonyms : Mixed lineage kinase domain like protein; FLJ34389

Application:

Reactivity : Human

Host species : Mouse

Conjugation/Formulation:PBS Only

  • Background Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
  • Immunogen Synthetic peptide conjugated to KLH
  • Gene ID 197259
  • Swiss Prot Q8NB16
  • Synonyms Mixed lineage kinase domain like protein; FLJ34389
  • Reactivity Human
  • Application IHC-P
  • Calculated MW 54 kDa
  • Host species Mouse
  • Clonality Monoclonal
  • Clonality No. 5E3-6B4-7G9
  • Isotype IgG1
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Immunohistochemistry analysis of paraffin-embedded Human Tonsil Tissue using MLKL (5E3) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Immunohistochemical analysis of paraffin-embedded Human tonsils using MLKL (5E3) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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  • 货期:现货
For research use only. Not intended for diagnostic.