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Bcl2 (9A4) Mouse mAb (PBS Only)
db6598-PBS
Datasheet

Product Name : Bcl2 (9A4) Mouse mAb (PBS Only)

Cat.No.: db6598-PBS

Synonyms : BCL2; Apoptosis regulator Bcl-2

Application:

Reactivity : Human, Rat, Mouse

Host species : Mouse

Conjugation/Formulation:PBS Only

  • Background Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed/17418785).
  • Immunogen Synthetic peptide conjugated to KLH
  • Gene ID 596
  • Swiss Prot P10415
  • Synonyms BCL2; Apoptosis regulator Bcl-2
  • Reactivity Human, Rat, Mouse
  • Application WB
  • Calculated MW 26 kDa
  • Observed MW 26 kDa
  • Host species Mouse
  • Clonality Monoclonal
  • Clonality No. 9A4-8B3-6E8
  • Isotype IgG1
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Western blot analysis of BCL2(2C12) in THP-1 lysates using BCL2 mouse Monoclonal Anbitoy(2C12) antibody.
订购信息
  • Package Price (RMB)
  • 可询价
  • 货期:现货
For research use only. Not intended for diagnostic.