Product Name : AMPK beta 1 Mouse mAb (PBS Only)
Cat.No.: db6601-PBS
Synonyms : 5''-AMP-activated protein kinase subunit beta-1; AMP-activated; noncatalytic; beta-1; AMPK; AMPK beta 1 chain; AMPK subunit beta-1; AMPK-BETA-1; AMPKb; HAMPKb; PRKAB1
Reactivity : Human
Host species : Mouse
Conjugation/Formulation：PBS Only
- Background Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes/ inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
- Immunogen Recombinant Protein of AMPKβ1
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Gene ID
5564
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Swiss Prot
Q9Y478
- Synonyms 5''-AMP-activated protein kinase subunit beta-1; AMP-activated; noncatalytic; beta-1; AMPK; AMPK beta 1 chain; AMPK subunit beta-1; AMPK-BETA-1; AMPKb; HAMPKb; PRKAB1
- Reactivity Human
- Application WB
- Calculated MW 30 kDa
- Observed MW 38 kDa
- Host species Mouse
- Clonality Monoclonal
- Clonality No. 2F2-4F9
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of AMPKβ1 in Hela, COS7 lysates using AMPK beta 1 antibody.
- Package Price (RMB)
- 可询价
- 货期：现货
