Product Name :
RAB7B Rabbit pAb
Cat.No.:
db7031
Synonyms :
RAB7
Reactivity :
Human, Mouse
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
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Background
Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.
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Immunogen
A synthetic peptide of human RAB7B
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Gene ID
338382
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Swiss Prot
Q96AH8
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Synonyms
RAB7
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Reactivity
Human, Mouse
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Application
WB, IHC, FC
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Recommended dilution
WB: 1:1000
IHC: 1:20
FC: 1:50
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Calculated MW
23 kDa
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Observed MW
23 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
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