UMOD Rabbit pAb - diagbio | 戴格生物

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UMOD Rabbit pAb

db7104

年底大促

Datasheet

Product Name : UMOD Rabbit pAb

Cat.No.: db7104

Synonyms : THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADMCKD2

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Immunogen Recombinant protein of human UMOD
Gene ID 7369
Swiss Prot P07911
Synonyms THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADMCKD2
Reactivity Human, Mouse, Rat
Application WB, IHC, IP
Recommended dilution WB: 1:1000
IHC: 1:200
IP: 1:20
Calculated MW 70 kDa
Observed MW 115 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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