Phospho-Rb2 p130 (Ser952) Rabbit pAb
Product Name :
Phospho-Rb2 p130 (Ser952) Rabbit pAb
Cat.No.:
db7405
Synonyms :
Rb2; P130
Reactivity :
Human, Mouse
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
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Background
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters.
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser952 of human Rb2 p130
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Gene ID
5934
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Swiss Prot
Q08999
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Synonyms
Rb2; P130
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Reactivity
Human, Mouse
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Application
WB, IHC, ICC/IF
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Recommended dilution
WB: 1:2000-1:10000
IHC: 1:20-1:100
ICC/IF: 1:20-1:100
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Calculated MW
128 kDa
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Observed MW
130 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
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