Product Name :
Girdin Rabbit pAb
Cat.No.:
db750
Synonyms :
APE; GIV; GRDN; PEHO; HkRP1; PEHOL; GIRDIN; KIAA1212
Application :
WB, ICC/IF, FC, IP
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
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Background
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
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Immunogen
Recombinant protein of human Girdin
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Gene ID
55704
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Swiss Prot
Q3V6T2
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Synonyms
APE; GIV; GRDN; PEHO; HkRP1; PEHOL; GIRDIN; KIAA1212
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Reactivity
Human, Mouse, Rat
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Application
WB, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000
ICC/IF: 1:200
FC: 1:20
IP: 1:20
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Calculated MW
216 kDa
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Observed MW
216 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期:现货
For research use only. Not intended for diagnostic.