Flt3,CD135 Rabbit pAb - diagbio | 戴格生物

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Flt3,CD135 Rabbit pAb

db7501

年底大促

Datasheet

Product Name : Flt3,CD135 Rabbit pAb

Cat.No.: db7501

Synonyms : FLK2; STK1; CD135; FLK-2

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]
Immunogen Recombinant protein of human CD135
Gene ID 2322
Swiss Prot P36888
Synonyms FLK2; STK1; CD135; FLK-2
Reactivity Human
Application WB, IP
Recommended dilution WB: 1:1000
IP: 1:20
Calculated MW 113 kDa
Observed MW 130-160 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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