Dysferlin Rabbit pAb - diagbio | 戴格生物

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Dysferlin Rabbit pAb

db7641

年底大促

Datasheet

Product Name : Dysferlin Rabbit pAb

Cat.No.: db7641

Synonyms : MMD1; FER1L1; LGMD2B

Application：

Reactivity : Human, Mouse

Host species : Rabbit

Un-conjugated

Background The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008]
Immunogen A synthetic peptide of human Dysferlin
Gene ID 8291
Swiss Prot O75923
Synonyms MMD1; FER1L1; LGMD2B
Reactivity Human, Mouse
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000
IHC: 1:100
ICC/IF: 1:50
Calculated MW 237 kDa
Observed MW 260 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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