Indoleamine 2,3-dioxygenase Rabbit pAb - diagbio | 戴格生物

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Indoleamine 2,3-dioxygenase Rabbit pAb

db7665

Datasheet

Product Name : Indoleamine 2,3-dioxygenase Rabbit pAb

Cat.No.: db7665

Synonyms : IDO; INDO; IDO-1

Application : WB, ICC/IF

Reactivity : Human

Host species : Rabbit

Background This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
Immunogen A synthetic peptide of human Indoleamine 2,3-dioxygenase
Gene ID 3620
Swiss Prot P14902
Synonyms IDO; INDO; IDO-1
Reactivity Human
Application WB, ICC/IF
Recommended dilution WB: 1:2000
ICC/IF: 1:20
Calculated MW 45 kDa
Observed MW 45 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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