Bcl10 Rabbit pAb - diagbio | 戴格生物

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Bcl10 Rabbit pAb

db7701

年底大促

Datasheet

Product Name : Bcl10 Rabbit pAb

Cat.No.: db7701

Synonyms : CLAP; mE10; CIPER; IMD37; c-E10; CARMEN

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Immunogen A synthetic peptide of human Bcl10
Gene ID 8915
Swiss Prot O95999
Synonyms CLAP; mE10; CIPER; IMD37; c-E10; CARMEN
Reactivity Human
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:20
ICC/IF: 1:50
FC: 1:50
IP: 1:20
Calculated MW 26 kDa
Observed MW 26 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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