Fibrillarin Rabbit pAb - diagbio | 戴格生物

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Fibrillarin Rabbit pAb

db7746

Datasheet

Product Name : Fibrillarin Rabbit pAb

Cat.No.: db7746

Synonyms : FIB; FLRN; Nop1; RNU3IP1

Application : WB, ICC/IF, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Fibrillarin
Gene ID 2091
Swiss Prot P22087
Synonyms FIB; FLRN; Nop1; RNU3IP1
Reactivity Human, Mouse, Rat
Application WB, ICC/IF, FC
Recommended dilution WB: 1:1000
ICC/IF: 1:500
FC: 1:20
Calculated MW 34 kDa
Observed MW 34 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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