Collagen XVII Rabbit pAb - diagbio | 戴格生物

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Collagen XVII Rabbit pAb

db777

年底大促

Datasheet

Product Name : Collagen XVII Rabbit pAb

Cat.No.: db777

Synonyms : ERED; BP180; BPA-2; BPAG2; LAD-1; BA16H23.2

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated Un-conjugated Un-conjugated Un-conjugated

Background This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Collagen XVII
Gene ID 1308
Swiss Prot Q9UMD9
Synonyms ERED; BP180; BPA-2; BPAG2; LAD-1; BA16H23.2
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, IP
Recommended dilution WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
IP: 1:20
Calculated MW 150 kDa
Observed MW 180,130 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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