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Proteasome 20S LMP2 Rabbit pAb

Product Name : Proteasome 20S LMP2 Rabbit pAb

Cat.No.: db7787

Synonyms : LMP2; PSMB6i; RING12; beta1i

Application:

Reactivity : Human

Host species : Rabbit

Conjugation/Formulation:Un-conjugated

  • Background The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. [provided by RefSeq, Mar 2010]
  • Immunogen A synthetic peptide of human Proteasome 20S LMP2
  • Gene ID 5698
  • Swiss Prot P28065
  • Synonyms LMP2; PSMB6i; RING12; beta1i
  • Reactivity Human
  • Application WB, ICC/IF, FC, IP
  • Recommended dilution WB: 1:1000
    ICC/IF: 1:20
    FC: 1:20
    IP: 1:20
  • Calculated MW 23 kDa
  • Observed MW 23 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 598
  • 50μL 998
  • 100μL 1798
  • 货期:现货
For research use only. Not intended for diagnostic.