BIN1 Rabbit pAb - diagbio | 戴格生物

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BIN1 Rabbit pAb

db7789

年底大促

Datasheet

Product Name : BIN1 Rabbit pAb

Cat.No.: db7789

Synonyms : CNM2; AMPH2; AMPHL; SH3P9

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Mar 2016]
Immunogen Recombinant protein of human BIN1
Gene ID 274
Swiss Prot O00499
Synonyms CNM2; AMPH2; AMPHL; SH3P9
Reactivity Human
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:20
ICC/IF: 1:50
FC: 1:20
IP: 1:20
Calculated MW 65 kDa
Observed MW 45-80 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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