ErbB 4 Rabbit pAb - diagbio | 戴格生物

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ErbB 4 Rabbit pAb

db7900

年底大促

Datasheet

Product Name : ErbB 4 Rabbit pAb

Cat.No.: db7900

Synonyms : HER4; ALS19; p180erbB4

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human ErbB 4
Gene ID 2066
Swiss Prot Q15303
Synonyms HER4; ALS19; p180erbB4
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 147 kDa
Observed MW 180 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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