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Conjugation/Formulation：Un-conjugated
- Background The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
- Immunogen A synthetic peptide of human FUBP1
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Gene ID
8880
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Swiss Prot
Q96AE4
- Synonyms FBP; FUBP; hDH V
- Reactivity Human, Mouse, Rat
- Application WB, IHC, ICC/IF, FC
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Recommended dilution
WB: 1:1000-1:5000
IHC: 1:50
ICC/IF: 1:50
FC: 1:20 - Calculated MW 68 kDa
- Observed MW 74 kDa
- Host species Rabbit
- Clonality Polyclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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订购信息
- Package Price (RMB)
- 20μL 598
- 50μL 998
- 100μL 1798
- 货期：现货
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For research use only. Not intended for diagnostic.
