Granulin Rabbit pAb - diagbio | 戴格生物

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Granulin Rabbit pAb

db8264

年底大促

Datasheet

Product Name : Granulin Rabbit pAb

Cat.No.: db8264

Synonyms : GEP; GP88; PEPI; PGRN; CLN11; PCDGF

Application：

Reactivity : Mouse

Host species : Rabbit

Un-conjugated

Background Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human Granulin
Gene ID 2896
Swiss Prot P28799
Synonyms GEP; GP88; PEPI; PGRN; CLN11; PCDGF
Reactivity Mouse
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:200
ICC/IF: 1:20
FC: 1:200
IP: 1:20
Calculated MW 64 kDa
Observed MW 55,88 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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