non-muscle Myosin IIA Rabbit pAb - diagbio | 戴格生物

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non-muscle Myosin IIA Rabbit pAb

db8410

Datasheet

Product Name : non-muscle Myosin IIA Rabbit pAb

Cat.No.: db8410

Synonyms : MHA; FTNS; EPSTS; BDPLT6; DFNA17; NMMHCA; NMHC-II-A; NMMHC-IIA

Application : WB, IHC, ICC/IF, FC

Reactivity : Human

Host species : Rabbit

Background This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]
Immunogen A synthetic peptide of human non-muscle Myosin IIA
Gene ID 4627
Swiss Prot P35579
Synonyms MHA; FTNS; EPSTS; BDPLT6; DFNA17; NMMHCA; NMHC-II-A; NMMHC-IIA
Reactivity Human
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:1000-1:5000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
FC: 1:20
Calculated MW 227 kDa
Observed MW 227 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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