Melanoma gp100 Rabbit pAb - diagbio | 戴格生物

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Melanoma gp100 Rabbit pAb

db8679

年底大促

Datasheet

Product Name : Melanoma gp100 Rabbit pAb

Cat.No.: db8679

Synonyms : P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
Immunogen A synthetic peptide of human Melanoma gp100
Gene ID 6490
Swiss Prot P40967
Synonyms P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E
Reactivity Human
Application WB, IHC
Recommended dilution WB: 1:1000
IHC: 1:200-1:500
Calculated MW 70 kDa
Observed MW 100 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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