NOTCH4 Rabbit pAb - diagbio | 戴格生物

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NOTCH4 Rabbit pAb

db8681

年底大促

Datasheet

Product Name : NOTCH4 Rabbit pAb

Cat.No.: db8681

Synonyms : INT3

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Immunogen A synthetic peptide of human NOTCH4
Gene ID 4855
Swiss Prot Q99466
Synonyms INT3
Reactivity Human
Application WB
Recommended dilution WB: 1:2000-1:10000
Calculated MW 36 kDa
Observed MW 36 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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