MASP1 Rabbit pAb - diagbio | 戴格生物

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MASP1 Rabbit pAb

db9512

年底大促

Datasheet

Product Name : MASP1 Rabbit pAb

Cat.No.: db9512

Synonyms : 3MC1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
Immunogen Recombinant protein of human MASP1
Gene ID 5648
Swiss Prot P48740
Synonyms 3MC1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1
Reactivity Human
Application WB, ICC/IF, FC
Recommended dilution WB: 1:1000
ICC/IF: 1:20
FC: 1:50
Calculated MW 79 kDa
Observed MW 90 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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