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Caspase-3 Recombinant Rabbit mAb
db12058
Datasheet

Product Name : Caspase-3 Recombinant Rabbit mAb

Cat.No.: db12058

Synonyms : CPP32; SCA-1; CPP32B

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human

Host species : Rabbit

  • Background The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
  • Immunogen A synthetic peptide of human Caspase-3
  • Gene ID 836
  • Swiss Prot P42574
  • Synonyms CPP32; SCA-1; CPP32B
  • Reactivity Human
  • Application WB, IHC, ICC/IF, FC, IP
  • Recommended dilution WB: 1:1000
    IHC: 1:20
    ICC/IF: 1:20
    FC: 1:50
    IP: 1:20
  • Calculated MW 32 kDa
  • Observed MW 32,17 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of Caspase-3 in K562,Hela cell lysates using Caspase-3 antibody(1:1000 diluted).
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.