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TBK1 (DGR13924) Rabbit mAb (PBS Only)
db11086-PBS
Datasheet

Product Name : TBK1 (DGR13924) Rabbit mAb (PBS Only)

Cat.No.: db11086-PBS

Synonyms : NAK; T2K; FTDALS4

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation:PBS Only

  • Background The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]
  • Immunogen Recombinant protein of human TBK1
  • Gene ID 29110
  • Swiss Prot Q9UHD2
  • Synonyms NAK; T2K; FTDALS4
  • Reactivity Human,Mouse,Rat
  • Application WB, IHC-P, ICC/IF
  • Calculated MW 84 kDa
  • Observed MW 84 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR13924
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Western blot analysis of extracts from Jurkat, C6, CHO-K1, HeLa cells using db11086 at 1:1000.
  • Immunofluorescence analysis of HeLa cells labelling TBK1 with db11086.

    The cells were fixed with 4% PFA (10min, RT) followed by treatment with 0.1% Triton X-100 (10min, RT), and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with db11086 (1:100) at room temprature for 1h, followed by a further incubation at room temperature for 45min with Goat Anti Rabbit lgG (H+L)-AF488 (db10005, shown in green). Nuclear DNA was labeled in blue with DAPI.

    Control: Secondary antibody only.
订购信息
  • Package Price (RMB)
  • 10μg 1498
  • 100μg 4498
  • 货期:现货
For research use only. Not intended for diagnostic.